TG Therapeutics 2025 Earnings and BRIUMVI Data
Analysis based on 6 articles · First reported Jan 13, 2026 · Last updated Mar 09, 2026
The strong financial performance and positive 2026 guidance from TG Therapeutics, driven by the success of Ublituximab, are expected to positively impact investor confidence and potentially lead to an increase in TG Therapeutics' stock price. The continued expansion of Ublituximab's market and positive clinical data reinforce its position as a significant treatment for multiple sclerosis, benefiting the biotechnology and pharmaceutical industries.
TG Therapeutics announced its financial results for the fourth quarter and full year ended December 31, 2025, reporting total revenue of $616.3 million for the full year, including $594.1 million in U.S. net revenue for Ublituximab. The company provided strong 2026 financial guidance, targeting $875-900 million in total global revenue. Alongside the earnings report, TG Therapeutics presented new data for Ublituximab at the ACTRIMS annual forum, including updates from real-world studies and designs for pediatric trials. The company also published five-year efficacy and safety data from the ULTIMATE I and II studies in JAMA Neurology and a post hoc analysis in Neurology and Therapy, further supporting Ublituximab's effectiveness in treating relapsing multiple sclerosis. Additionally, TG Therapeutics launched the 'Next In MS' platform in collaboration with Christina Applegate to raise awareness for multiple sclerosis and completed a $100 million share repurchase program, authorizing a new one.
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