Tiziana Foralumab na-SPMS Clinical Data
Analysis based on 6 articles · First reported May 19, 2026 · Last updated May 19, 2026
The positive clinical data for Foralumab could lead to increased investor confidence in Tiziana Life Sciences, potentially boosting its stock price. This development also signals progress in the treatment of Secondary Progressive Multiple Sclerosis, which could impact the broader biotechnology and pharmaceutical industries.
Tiziana Life Sciences announced updated positive clinical data from its Expanded Access Program for intranasal Foralumab, its lead candidate for non-active Secondary Progressive Multiple Sclerosis (na-SPMS). The data, collected from March 2025 to March 2026, showed that Foralumab was well tolerated and demonstrated encouraging trends in stabilizing disability and improving fatigue in 14 patients. Specifically, 64% of patients achieved a clinically meaningful improvement in their Modified Fatigue Impact Scale (MFIS) score. While the small sample size means the results are not statistically significant and represent a trend analysis only, key figures like Howard L. Weiner and Ivor Elrifi expressed strong support for the drug's potential as a novel immunomodulatory therapy and its advancement towards approval.
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