Rejuvant outperforms supplements in aging study
Analysis based on 6 articles · First reported May 28, 2026 · Last updated May 29, 2026
The positive results for Rejuvant in an independent study published in Cellular senescence are expected to significantly boost investor confidence in Ponce de Leon Health and the longevity supplement market. This could lead to increased sales and market share for Rejuvant, potentially impacting the stock prices of publicly traded companies in the nutraceutical and biotechnology sectors as investors seek similar opportunities.
Ponce de Leon Health announced the publication of a landmark peer-reviewed study in the scientific journal Cellular senescence. The independent study, which was not sponsored by Ponce de Leon Health, compared 84 commonly used supplements and drugs for their effect on biologic age in over 4,000 subjects. Rejuvant, a commercially available supplement from Ponce de Leon Health, was the only compound to achieve statistical significance, showing an average 1.8-year lower age residual. Other supplements, including standard CaAKG/AKG and NAD+ forms, were significantly less effective and statistically insignificant. Dr. Brian Kennedy (biogerontologist) and Dr. Nir Barzilai both provided positive endorsements for Rejuvant's effectiveness and plausible mechanism of action.
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