Cellectis Presents Positive CAR-T Trial Data
Analysis based on 7 articles · First reported Jun 11, 2026 · Last updated Jun 11, 2026
The positive Phase 1 results for lasme-cel and eti-cel from Cellectis are likely to positively impact the stock price of Cellectis, as these therapies show promise for difficult-to-treat cancers. This could also attract further investment in the biotechnology sector, particularly in gene-editing and CAR-T therapies.
Cellectis, a clinical-stage biotechnology company, presented final Phase 1 data for lasme-cel in relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) and preliminary data for eti-cel in relapsed/refractory B-cell non-Hodgkin lymphoma (r/r B-NHL) at the European Hematology Association (EHA) 2026 Annual Congress. The BALLI-01 trial for lasme-cel showed a 100% overall response rate and a manageable safety profile, with 75% of responders achieving minimal residual disease negative status. Nitin Jain, M.D., from the MD Anderson Cancer Center, highlighted the significance of these results for patients with limited treatment options. The NATHALI-01 trial for eti-cel demonstrated an 88% overall response rate and a 63% complete response rate in the optimal dose cohort, with Professor Emmanuel Bachy, M.D., Ph.D., from Hospices Civils de Lyon, noting the positive correlation between alemtuzumab exposure and clinical outcomes. Both trials are open for further recruitment, with interim analysis for BALLI-01 expected in Q4 2026 and full Phase 1 data for NATHALI-01 also expected in Q4 2026.
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