Post-menopausal ovary immune role

A study published in Human Reproduction (journal) by researchers at Northwestern University, led by Francesca Duncan and including Aubrey Converse, found that ovaries in mice undergo a functional transition after menopause, shifting from reproductive to immune-like activity. The post-reproductive ovaries showed increased immune cell infiltration and activation of inflammatory genes, challenging the long-held assumption that they become inert. The study suggests potential implications for understanding aging and women's health, though human confirmation is needed.