Nurix-Roche bexobrutideg collaboration closed
Analysis based on 6 articles · First reported Jul 21, 2026 · Last updated Jul 21, 2026
The collaboration provides Nurix with substantial non-dilutive funding and validates its protein degradation platform, likely boosting its stock. Roche gains access to a promising best-in-class asset, strengthening its pipeline in multiple therapeutic areas.
Nurix Therapeutics announced the closing of its global collaboration agreement with Roche to co-develop and co-commercialize bexobrutideg, a BTK degrader, after HSR clearance. Nurix received a $700 million upfront payment and is eligible for up to $2.3 billion in milestones. Development costs are shared 40% Nurix and 60% Roche, with equal U.S. profit/loss split and tiered royalties outside the U.S. The partnership aims to advance bexobrutideg across oncology, immunology, and neurology.
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