International AIDS Vaccine Initiative & World Health Organization

International AIDS Vaccine Initiative: The International AIDS Vaccine Initiative is working on a modified version of the Zaire Ebola vaccine to fight the Bundibugyo strain, with experimental jabs showing nearly 100% protection in monkeys.

World Health Organization: The World Health Organization is leading the international response to the Ebola outbreak in the Democratic Republic of the Congo, revising its risk assessment to 'very high' nationally and launching a $518 million plan to combat the spread. Its efforts are hampered by conflict and community mistrust.

International AIDS Vaccine Initiative: The International AIDS Vaccine Initiative is developing rVSV Bundibugyo, a single-dose vaccine candidate seen as promising by the World Health Organization, though it is not yet ready for trials.

World Health Organization: The World Health Organization recommended prioritizing three experimental treatments and several vaccine candidates for the Bundibugyo strain of Ebola, and is working with authorities to design and implement clinical trials.

International AIDS Vaccine Initiative: The International AIDS Vaccine Initiative (IAVI) received an initial $3.2 million from CEPI to develop a single-dose Bundibugyo vaccine candidate using technology similar to Merck's Ervebo.

World Health Organization: The World Health Organization (WHO) has declared the outbreak a public health emergency and is involved in monitoring cases and coordinating the global health response.

International AIDS Vaccine Initiative: Developing a single-dose Bundibugyo vaccine candidate, which is being prioritized for clinical evaluation. Their work could provide an alternative vaccine.

World Health Organization: Leading the international response, declaring a PHEIC, recommending vaccine trials, and adding a diagnostic test to its Emergency Use Listing. Its credibility is tied to the success of the response.

International AIDS Vaccine Initiative: The International AIDS Vaccine Initiative is developing a Bundibugyo-specific version of a vaccine using a platform similar to Merck & Co.'s Ervebo vaccine, contributing to the search for a treatment.

World Health Organization: The World Health Organization>>> has declared the Ebola outbreak a public health emergency of international concern and is coordinating the international response, providing experts, supplies, and guidance, though it faces criticism for delayed detection and underestimation of the outbreak's scale.

International AIDS Vaccine Initiative: Partner in vaccine development efforts.

World Health Organization: Leading the international response, coordinating clinical trials, and issuing warnings; faces criticism over response speed.